Composition comprising ubiquinone

Colloid systems and wetting agents; subcombinations thereof; pro – Continuous liquid or supercritical phase: colloid systems;... – Aqueous continuous liquid phase and discontinuous phase...

Reexamination Certificate

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Details

C516S072000, C424S094100, C514S937000, C426S072000, C426S311000

Reexamination Certificate

active

07026361

ABSTRACT:
This invention relates to a composition comprising ubiquinone having superior dispersion-stability in an aqueous solution and high bioavailability. The ubiquinone(s) is dispersed and emulsified in an aqueous solution of a water-soluble material in the presence of an organic acid(s) to form a protective colloid, the average particle size of the suspended particles being not more than 5 μm. The liquid composition can be adsorbed in or carried on an excipient, or dried.

REFERENCES:
patent: 4540602 (1985-09-01), Motoyama et al.
patent: 4751241 (1988-06-01), Motoyama et al.
patent: 4767624 (1988-08-01), Okuyama et al.
patent: 5298246 (1994-03-01), Yano et al.
patent: 5540942 (1996-07-01), Tokoro
patent: 0 522 433 (1993-01-01), None
patent: 57-4916 (1982-01-01), None
patent: 59-51214 (1984-03-01), None
Machine translation of JP 05078240A, Japan Patent Office (6 pages), http://www6.ipdl.jpo.go.jp/Tokujitu/PAJdetail.ipdl?N0000=80&N0120=01&N2001=2&N3001=H05-078240 (Sep. 2003).
English language Translation of JP 59-161314, PTO-03-[5416], (USPTO, Wash, DC, Sep. 2003), pp. 1-18.
The Merck Index An Encyclopedia of Chemicals, Drugs, and Biologicals, Tenth Edition, (Merck & Co, Inc. Rahway, NJ, 1983) p. 887, Jan. 17, 1984.
Hawley's Condensed Chemical Dictionary, Eleventh Edition, edited by Sax and Lewis, Sr. (Van Nostrand Reinhold Company, Ney York, NY, copyright 1987), Oct. 1989, p. 224-225 & 555-556.

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