Drug – bio-affecting and body treating compositions – Lymphokine
Patent
1992-10-05
1995-06-27
Draper, Garnette D.
Drug, bio-affecting and body treating compositions
Lymphokine
530399, 530351, 514 12, C07K 1500, A61K 3702
Patent
active
054277809
ABSTRACT:
Mullerian Inhibiting Substance (MIS)-like polypeptide are described. The MIS-like polypeptides are useful in the treatment of ovarian cancer and other susceptible cancers.
REFERENCES:
patent: 4289690 (1981-09-01), Pestka et al.
patent: 4404188 (1983-09-01), Donahoe et al.
patent: 4442205 (1984-04-01), Hamer et al.
patent: 4487833 (1984-12-01), Donahoe et al.
patent: 4510131 (1985-04-01), Donahoe et al.
patent: 4740587 (1988-04-01), Ling et al.
patent: 4753794 (1988-06-01), Donahoe
patent: 4792601 (1988-12-01), Donahoe et al.
patent: 5010055 (1991-04-01), Donahoe
patent: 5011687 (1991-04-01), Donahoe et al.
patent: 5047336 (1991-09-01), Cate et al.
patent: 5198420 (1993-03-01), Donahoe et al.
Hird et al. Genes and Cancer pp. 183-189 (1990).
Bowie et al Science 247:1306-1310 (1990).
Chem. Abstr. vol. 99 (1983) 116305.
Chem. Abstr. vol. 90 (1979) 199833.
Chem. Abstr. vol. 107 (1987) 230569.
Chem. Abstr. vol. 107 (1987) 110364.
M. G. Blanchard et al., "Source of The Anti-Mullerian Hormone Synthesized By The Fetal Testis: Mullerian-Inhibiting Activity Of Fetal Bovine Sertoli Cells In Tissue Culture", Pediat. Res., 8, 968-971 (1974).
G. Budzik et al., "Enhanced Purification Of Mullerian Inhibiting Substance By Lectin Affinity Chromatography", Cell, 21, 909-915 (1980) [Budzik et al. I].
G. Budzik et al., "A Possible Purification Of Mullerian Inhibiting Substance And A Model For Its Mechanism Of Action", Developmental Mechanisms: Normal and Abnormal, 171, 207-223 (1985) [Budzik et al. II].
R. L. Cate et al., "Isolation Of The Bovine And Human Genes For Mullerian Inhibiting Substance And Expression Of The Human Gene In Animal Cells", Cell, 45, pp. 685-698 (1986).
P. Donahoe et al., "The Production Of Mullerian Inhibiting Substance By The Fetal, Neonatal And Adult Rat", Biology of Reproduction, 15, 329-334 (1976) [Donahoe et al. I].
P. Donahoe et al., "Mullerian Inhibiting Substance Activity In Bovine Fetal, Newborn And Prepubertal Testes", Biology of Reproduction, 16, 238-243 (1977) [Donahoe et al. II].
P. Donahoe et al., "Mullerian Inhibiting Substance In Human Testes After Birth", Journal of Pediatric Surgery, 12, 323-330 (1977) [Donahoe et al. III].
P. Donahoe et al., "Mullerian Duct Regression In The Embryo Correlated With Cytotoxic Activity Against Human Ovarian Cancer", Science, 205, 913-915 (1979) [Donahoe et al. IV].
P. Donahoe et al., "Mullerian Inhibiting Substance Inhibits Growth Of A Human Ovarian Cancer In Nude Mice", Ann. Surg., 194, 472-480 (1981) [Donahoe et al. V].
P. Donahoe et al., "The Biochemistry And Biology Of Mullerian Inhibiting Substance", Pediatric Andrology, 37-46, 1981 [Donahoe et al. VI].
P. Donahoe et al., "Mullerian-Inhibiting Substance: An Update", Recent Progress In Hormone Research, 38, 279-330 (1982). [Donahoe et al. VII].
P. Donahoe et al., "Mechanism Of Action Of Mullerian Inhibiting Substance", Ann. Rev. Physiol., 46, 53-65 (1984). [Donahoe et al. VIII].
P. Donahoe et al., "Molecular Dissection Of Mullerian Duct Regression", The Role of Extracellular Matrix in Development, 573-595 (1984) [Donahoe et al. IX].
M. Fallat et al., "The Role of Nucleotide Pyrophosphatase In Mullerian Duct Regression", Developmental Biology, 100, 358-364 (1983) [Fallat et al. I].
M. Fallat et al., "Androgen Stimulation Of Nucelotide Pyrophosphatase During Mullerian Duct Regression", Endocrinology, 114, 1592-1598 (1984) [Fallat et al. II].
A. Fuller, Jr. et al., "Mullerian Inhibiting Substance Inhibits Colony Growth Of A Human Ovarian Carcinoma Cell Line", J. Clin. Endocr. Met., 54, 1051-1055 (1982) [Fuller et al. I].
A. Fuller, Jr. et al., "Mullerian Inhibiting Substance Inhibition Of A Human Endometrial Carcinoma Cell Line Xenografted In Nude Mice", Gynecologic Oncology, 17, 124-132 (1984) [Fuller et al. II].
A. Fuller, Jr. et al., "Mullerian Inhibiting Substance Reduction Of Colony Growth Of Human Gynecologic Cancers In A Stem Cell Assay", Gynecologic Oncology, 22, 135-148 (1985) [Fuller et al. III].
M. Hayashi et al., "Immunocytochemical Localization Of Mullerian Inhibiting Substance In The Rough Endoplasmic Reticulum And Golgi Apparatus In Sertoli Cells Of The Neonatal Calf Testis Using A Monoclonal Antibody", Journal of Histochemistry and Cytochemistry, 32, 649-654 (1984).
J. Hutson et al., "The Ontogeny Of Mullerian Inhibiting Substance In The Gonads Of The Chicken", J. Pediatric Surgery, 16, 822-827 (1981) [Hutson et al. I].
J. Hutson et al., "Phosphorylation Events During Mullerian Duct Regression", Science, 223, 586-589, (1984) [Hutson et al. II].
J. Hutson et al., "Steroid Modulation Of Mullerian Duct Regression In The Chick Embryo", General and Comparative Endocrinology, 57, 88-102 (1985) [Hutson et al. III].
H. Ikawa et al., "Steroid Enhancement Of Mullerian Duct Regression", J. Pediatric Surgery, 17, 453-458 (1982) [Ikawa et al. I].
H. Ikawa et al., "Cyclic Adenosine 3',5'-Monophosphate Modulation Of Mullerian Duct Regression", Endocrinology, 114, 1686-1691 (1984) [Ikawa et al. II].
M. Jaye et al., "Isolation Of A Human Anti-Haemophilic Factor IX cDNA Clone Using A Unique 52-Base Synthetic Oligonucleotide Probe Deduced From The Amino Acid Sequence Of Bovine Factor IX", Nucleic Acids Research, 11, pp. 2325-2335 (1983).
N. Josso, "Permeability Of Membranes To The Mullerian-Inhibiting Substance Synthesized By The Human Fetal Testis in Vitro: A Clue To Its Biochemical Nature", J. Clin. Endocr., 34, 265-270 (1972) [Josso I].
N. Josso, "In Vitro Synthesis Of Mullerian-Inhibiting Hormone By Seminiferous Tubules Isolated From The Calf Fetal Testis", Endocrinology, 93, 829-834 (1973) [Josso II].
N. Josso et al., "Mullerian-Inhibiting Activity Of Calf Fetal Testes: Relationship To Testosterone And Protein Synthesis", Biology of Reproduction, 13, 153-167 (1975).
D. MacLaughlin et al., "Specific Estradiol Binding In Embryonic Mullerian Ducts: A Potential Modulator Of Regression In The Male And Female Chick", Endocrinology, 113, 141-145 (1983).
M. Mudgett-Hunter et al., "Monoclonal Antibody To Mullerian Inhibiting Substance", Journal of Immunology, 128, 1327-1333 (1982).
E. C. Necklaws et al., "Detection Of Mullerian Inhibiting Substance In Biological Samples By A Solid Phase Sandwich Radioimmunoassay", Endocrinology, 118, pp. 791-796 (1986).
J.-Y. Picard et al., "Anti-Mullerian Hormone: Estimation Of Molecular Weight By Gel Filtration", Biomedicine, 25, 147-150 (1976) [Picard et al. I].
J-Y Picard et al., "Biosynthesis Of Labelled Anti-Mullerian Hormone By Fetal Testes: Evidence For The Glycoprotein Nature Of The Hormone And For Its Disulfide-Bonded Structure", Molecular and Cellular Endocrinology, 12, 17-30, (1978) [Picard et al. II].
J-Y Picard et al., "Purification Of Testicular Anti-Mullerian Hormone Allowing Direct Visualization Of The Pure Glycoprotein And Determination Of Yield And Purification Factor", Molecular and Cellular Endocrinology, 34, pp. 23-29 (1984) [Picard et al. III].
Z. Rosenwaks et al., "In Vitro Inhibition Of Endometrial Cancer Growth By A Neonatal Rat Testicular Secretory Product", J. Clin. Endocr. Met., 52, 817-819 (1981).
SCRIP, No. 976, p. 22, Feb. 25, 1985.
H. Shima et al., "Production Of Monoclonal Antibodies For Affinity Purification Of Bovine Mullerian Inhibiting Substance Activity", Hybridoma, 3, 201-214 (1984).
B. Vigier et al., "A Monoclonal Antibody Against Bovine Anti-Mullerian Hormone", Endocrinology, 110, 131-137 (1982) [Vigier et al. I].
B. Vigier et al., "Production Of Anti-Mullerian Hormone: Another Homology Between Sertoli And Granulosa Cells", Endocrinology, 114, 1315-1320 (1984) [Vigier et al. II].
Cate Richard L.
Donahoe Patricia K.
Biogen Inc.
Cermak Shelly Guest
Draper Garnette D.
The General Hospital Corporation
LandOfFree
Composition comprising Mullerian inhibiting substance-like polyp does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Composition comprising Mullerian inhibiting substance-like polyp, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Composition comprising Mullerian inhibiting substance-like polyp will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-285529