Composition comprising L-dopa

Details Composition comprising L-dopa Composition comprising L-dopa

1989-07-12

1991-01-01

Bell, Mark L.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

424463, 424494, 514252, 514781, 514962, 514963, 514964, 514965, A61K 954, A61K 916

Patent

active

049816950

ABSTRACT:
The present invention relates to a multiple-unit-dose comprising L-dopa as pharmaceutically active compound, whereby the composition provides a release of L-dopa in accordance with a test in accordance with U.S. Pharmacopeia Standards in an artificial gastric juice having a pH of at most 1.2 of at most 20% by weight during 1 hr, and in a phosphate buffer according to the same standard a release of at least 35% by weight during 1 hr, and at least 80% by weight during 3 hrs.

REFERENCES:
patent: 3957523 (1976-05-01), Ohno et al.
patent: 4021555 (1977-05-01), Seyfried et al.
patent: 4446138 (1984-05-01), Pack

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