Composition comprising coagulation factor VIII formulation, proc

Details Composition comprising coagulation factor VIII formulation, proc Composition comprising coagulation factor VIII formulation, proc

1997-05-27

1999-07-06

Degen, Nancy

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 2, 514 12, 514834, 530380, 530381, 530383, A61K 3837, A61K 3836, C07K 1447, C07K 14755

Patent

active

059197668

ABSTRACT:
The present invention relates to a novel composition comprising coagulation Factor VIII and a non-ionic surfactant such as block co-polymers, e.g. polyoxamers or polyoxyethylene (20) fatty acid esters e.g. polysorbate 20 or polysorbate 80 as a stabilizer. The composition can also comprise sodium chloride, calcium chloride, L-histidine and/or sugars or sugar alcohols.

REFERENCES:
patent: 4165370 (1979-08-01), Coval
patent: 4783441 (1988-11-01), Thurow
patent: 4877608 (1989-10-01), Lee et al.
patent: 5118794 (1992-06-01), Grandgeorge et al.
patent: 5328694 (1994-07-01), Schwinn et al.
patent: 5733873 (1998-03-01), Osterberg et al.

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