Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1994-06-30
1995-11-21
Henley, III, Raymond
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514646, A61K 31485, A61K 31135
Patent
active
054687446
ABSTRACT:
This invention relates to compositions comprising a tramadol material selected from the group consisting of tramadol, its stereoisomers and its pharmaceutically acceptable salts and either codeine or oxycodone, and their use in treating pain. When the components, i.e., tramadol materials and either of codeine or oxycodone, of the composition are within certain ratios of pharmacological effects of the compositions are superaddditive (synergistic).
REFERENCES:
patent: 3652589, Flick et al.
Raffa Robert B.
Vaught Jeffrey L.
Henley III Raymond
Jarvis William R. A.
McNeil Lab, Inc.
Palo Ralph R.
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