Composition comprising a tramadol material and a non-steroidal a

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...

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Details

514646, A61K 3119, A61K 31135

Patent

active

055168035

ABSTRACT:
This invention relates to a composition comprising a tramadol material and a nonsteroidal antiinflammatory drug, and its use. The compositions are pharmacologically useful in treating pain and tussive conditions. The compositions are also subject to less opioid side-effects such as abuse liability, tolerance, constipation and respiratory depression. Furthermore, where the components of the compositions are within certain ratios the pharmacological effects of the compositions are superadditive (synergistic).

REFERENCES:
patent: 3652589 (1972-03-01), Flick et al.
patent: 4939145 (1990-07-01), Lau et al.

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