Composition and process for gelatin-free soft capsules

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Capsules

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Details

514777, 514780, 514962, 426573, 156246, 53454, A61K 962

Patent

active

053426266

ABSTRACT:
The present invention relates to a polymer composition comprised of gellan, carrageenan and mannan gums and a process for producing flexible films for encapsulation comprising the gellan, carrageenan and mannan gum composition. The mannan gums include the galactomannans and the glucomannans. Advantageously, soft capsules of the above composition are produced using the novel process. The composition comprises a blend of a gellan gum: (carrageenan/mannan gum) wherein the gellan gum concentration ranges from about 0.1 to 50 weight percent and the ratio of carrageenan/locust bean gum ranges from 3:1 to 1:3. Additional reagents are added to this gum blend to form a film-forming polymer composition useful in the production of gelatin-free capsules or microcapsules.

REFERENCES:
patent: 4326052 (1982-04-01), Kang et al.
patent: 4326053 (1982-04-01), Kang et al.
patent: 4377636 (1983-03-01), Kang et al.
patent: 4385123 (1983-05-01), Kang et al.
patent: 4647470 (1987-03-01), Sanderson et al.
patent: 4746528 (1988-05-01), Prest et al.
patent: 5112445 (1992-05-01), Winston et al.

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