Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1975-02-07
1976-11-30
Jiles, Henry R.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
260296T, C07D48704
Patent
active
039950433
ABSTRACT:
Pharmaceutical compositions comprising, in unit dosage form, from about 0.5 mg. to about 100 mg. of a compound of the formula ##SPC1##
Wherein R and R' are hydrogen, methyl or ethyl, R.sub.1 is hydrogen or lower alkyl of 1 through 3 carbon atoms, R.sub.2 is hydrogen, lower alkyl of 1 through 3 carbon atoms, fluorine, chlorine, bromine, nitro, trifluoromethyl or lower alkylthio of 1 through 3 carbon atoms, and the pharmacologically acceptable acid addition salts thereof, in association with a pharmaceutical carrier. The process is the administration of the above compositions to humans or animals at a dose of from about 0.01 mg./kg./day to about 2 mg./kg./day for anti-anxiety or anti-depressant effects.
REFERENCES:
patent: 3734922 (1973-05-01), Hester
Chem. Abst. 78: 136353k (5-28-73).
Jaisle C.
Jiles Henry R.
Reynolds John T.
The Upjohn Company
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