Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Web – sheet or filament bases; compositions of bandages; or...
Patent
1997-05-27
2000-02-15
Dees, Jose' G.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Web, sheet or filament bases; compositions of bandages; or...
424486, 424487, 514946, 514947, 5147725, A61F 1302
Patent
active
060249749
ABSTRACT:
A transdermal composition and related method are described. Specifically, the transdermal composition is substantially free of gestodene or substantially free of isopropyl myristate and substantially free of lower alkanols and comprises: (a) a therapeutically effective amount of a pharmacologically active drug which is subject to acid catalyzed degradation; (b) a pharmaceutically acceptable carrier; and (c) a penetration enhancing effective amount of a functional derivative of a fatty acid.
REFERENCES:
patent: 4537776 (1985-08-01), Cooper
patent: 4863970 (1989-09-01), Patel et al.
patent: 5162315 (1992-11-01), Rajadhyaksha et al.
patent: 5164190 (1992-11-01), Patel et al.
patent: 5212199 (1993-05-01), Heiber et al.
patent: 5225198 (1993-07-01), Sharma et al.
patent: 5252334 (1993-10-01), Chiang et al.
Aungst et al., "Contributions of Drug solubilization, Partitioning, Barrier Disruption and Solvent Permeation to the Enhancement of Skin Permeation of Various Compounds with fatty Acids and Amines," Pharmaceutical Research, vol. 7, No. 7, (1990) p. 712.
Cooper, "Increased Skin Permeability for Lipophilic Molecules," Journal of Pharmaceutical Sciences, vol. 73, No. 8 Aug. 1984 p. 1153.
Bialik et al., "The Effects of surfactants on Penetration Across the Skin," International Journal of Cosmetic Science, 15: 260-270 (1993).
Eugene Cooper, "Increased Skin Permeability for Lipophilic Molecules", Journal of Pharmaceutical Sciences, vol. 73, No. 8, pp. 1153-1156, 1984.
Dees Jos,e G.
Noven Pharmaceuticals Inc.,
Williamson Michael A.
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