Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1981-11-23
1985-10-22
Coughlan, Jr., Paul M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
544273, A61K 3152, C07D47306
Patent
active
045488185
ABSTRACT:
Compounds having activity against chronic obstructive airway disease or cardiac disease, characterized by the formula ##STR1## wherein R.sup.1 is n-propyl, n-butyl, isobutyl, n-pentyl, 2-methylbutyl, 3-methylbutyl, 2,2-dimethylpropyl, cyclopropyl, cyclobutyl, cyclopentyl or cyclohexylmethyl, and R.sup.2 is hydrogen or methyl, provided that R.sup.2 is methyl when R.sup.1 is n-propyl, n-butyl or isobutyl, or a physiologically acceptable salt thereof.
REFERENCES:
patent: 2646432 (1953-07-01), Homeyer et al.
patent: 2781344 (1957-02-01), Comte
patent: 2844576 (1958-07-01), Goldman et al.
patent: 4089959 (1978-05-01), Diamond
patent: 4120947 (1978-10-01), Diamond
patent: 4233303 (1980-11-01), Bergstrand et al.
patent: 4325956 (1982-04-01), Kjellin et al.
patent: 4338319 (1982-07-01), Kjellin et al.
Persson, et al., Acta pharmacol. et toxicol., vol. 49, pp. 317-320 (1981).
Persson, et al., Life Sciences, vol. 30, pp. 2181-2189 (1982).
Read, et al., Psychopharmacologica, vol. 1, pp. 346-350 (1960).
Ohtsuka, Chemical Abstracts, vol. 78, 124544k (1973).
Ohtuska, Chemical Abstracts, vol. 81, 152277f (1974).
Beavo, et al., Chemical Abstracts, vol. 74, 40820b (1971).
Kramer, et al., Chemical Abstracts, vol. 87, 98027h (1977).
LeRoy, J. Pharmacol. Exptl. Therap., 69, pp. 45-51 (1940).
Goldner, et al., Ann. Chem. 691, pp. 142-158 (1966).
Kattus, et al., Bull. Johns Hopkins Hospital (Balt.), 89, 1-8 (1951).
Kjellin Per G.
Persson Carl G. A.
Coughlan, Jr. Paul M.
Rivers Diana G.
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