Composition and methods for providing optimum bioavailability of

Details Composition and methods for providing optimum bioavailability of Composition and methods for providing optimum bioavailability of

1990-02-07

1992-01-07

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

514177, 514182, 514946, A61K 3115

Patent

active

050792652

ABSTRACT:
Improved bioavailability, particularly when the drug is administered orally, of the active ingredient 2-hydroxy-5-methyllaurophenoxime (HMLO) of a pharmaceutical preparation is achieved by improving the absorption of the active ingredient HMLO significantly by including bile acids in the preparation. As bile acids, it is possible to use, for example, desoxychloic acid or dehydrocholic acid or a mixture of the two in the form of their salts.

REFERENCES:
patent: 4816487 (1989-03-01), Schewe et al.
Chemical Abstracts 86:95918t (1977).
Chemical Abstracts 108:226,860r (1988).

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