Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2004-12-14
2010-11-30
Fay, Zohreh A (Department: 1612)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S725000, C514S912000
Reexamination Certificate
active
07842722
ABSTRACT:
The present invention provides improved dietary supplements and methods for inhibiting the progression of macular degeneration and promoting healthy vision. The dietary supplements of the invention contain cobeadlets comprising vitamin E and carotenoids in the form of Vitamin A, lutein and/or zeaxanthing. The dietary supplements of the invention further contain Vitamin C, copper and zinc and may also contain such ingredients as rosemary, DHA, other vitamins and minerals.
REFERENCES:
patent: 3998753 (1976-12-01), Antoshkiw et al.
patent: 4254100 (1981-03-01), Keller et al.
patent: 4657928 (1987-04-01), Sorenson
patent: 4670247 (1987-06-01), Scialpi
patent: 6582721 (2003-06-01), Lang
patent: 6649195 (2003-11-01), Gorsek
patent: 2002/0182266 (2002-12-01), Bartels et al.
patent: 2003/0064133 (2003-04-01), Blatt et al.
patent: 101 09 798 (2002-09-01), None
patent: WO 2005/065669 (2005-07-01), None
Areds Report No. 9, Age-Related Eye Disease Study Research Group: “A Randomized, Placebo-Controlled, Clinical Trial Of High-Dose Supplementation With Vitamins C And E And Beta Carotene For Age-Related Cateract and Vision Loss”, Archives Of Ophthalmology, 119(10):1439-1452 (2001).
Beem, J Biol Chem 249:7298 (1974).
Berman, Biochemistry of the Eye, (Plenum Press, 1991), 309-330, 345-359 and 386-399.
Bernstein et al., Retinal Tubulin Binds Macular Carotenoids, Inv Ophthal & Vis Sci 38(1):167-175 (1997).
Bone and Landrum, Am Society for Nutritional Sciences J Nutr, 133:992-998 (2003).
Chandler et al., J. Biol. Chem 261:928-33 (1986).
Chaney, Textbook of Biochemistry With Clinical Correlations, John Wiley & Sons, 970-971 (1986).
Chatterjee and Ghosh, Arch, Ophthalmol 56:756-60 (1956).
Fischer, J Nutrition 113:462-469 (1983).
Hammond et al., Sex differences in macular pigment optical density: relation to plasma carotenoid concentrations and dietary patterns, Vision Research 36:2001-2012 (1996a).
Hammond et al., Cigarette smoking and retinal carotenoids: implications for age-related macular degeneration, Vision Research 36:3003-3009 (1996b).
Hammond et al., Dietary Modification of Human Macular Pigment Diensity, Inv Ophthal & Vis Sci 38 (9):1795-1801 (1997).
Handelman et al., Biological Control of Primate Macular Pigment: Biochemical and Densitometric Studies, Inv Ophthal & Vis Sci 32(2):257-267 (1991).
Harris, Nature 132:27-8 (1993).
Hooper et al., JAMA 244:1960-1961 (1980).
Jacques et al., Antioxidant Status in Persons With and Without Senile Cateract, Arch. Ophthalm. 106:337-340 (1988).
Karcioglu, Surv Ophthalmol 27:114-122 (1982).
Leure-Dupree, Retina 2:294-302 (1982a).
Leure-Dupree, Invest Ophthalmol Vis Sci 23:425-34 (1982b).
Machlin et al., Free Radical Tissue Damage: Protective Role of Antioxidant Nutrients, FASEB J 1:441-445 (1987).
Mansour et al., Effect of Antioxidant (Vitamin E) On The Progress of Cataracts In Emory Mice, ARVO Abstract #47, p. 138 (1984 Supplement).
Newsome, D.A., Oral Zinc in Macular Degeneration, Arch. Ophthalmol. 106:192-198 (1988).
Ohrloff and Hockwin, Graefe's Arch Clin Exp Ophthalmol 222:79-81 (1984).
Orten, Human Biochemistry 10th Edition, CV Mosby Co., p. 756-757 (1982).
PCT International Search Report of the related PCT Application No. PCT/US2004/041813, mailed Jun. 13, 2005.
Pennington, J Am Dietetic Assoc 86:876-91 (1986).
Purcell et al., Arch Ophthalmol 51:1-6 (1968).
Ringvold, Acta, Ophthalmologica 63:227-2 80 (1985).
Russell, Ann Int Med 99:227-239 (1983).
Seddon et al., Dietary Carotenoids, Vitamins A, C and E, and Advanced Age-Related Macular Degeneration, JAMA 272(8):1413-1420 (1994).
Snodderly, Evidence for protection against age-related macular degeneration by carotenoids and antioxidant vitamins, Am J Clin Nutr 62(suppl):1448S-1461S (1995).
Sparrow et al., 2001, Bioorganic & Medicinal Chemistry Letters, 11, 1533-1540.
Spector et al., Exp. Eye Res. 33:673-681 (1981).
Swanson, Biochem Biphy Res Comm 45:1488-1496 (1971).
Van Campen, J Nutrition 97:104-108 (1970).
Varma et al., Ophthalmic Res 9:421-431 (1977).
Varma et al., Ophthalmic Res 26:141-148 (1994).
Wagner, Geriatrics 40:111-125 (1985).
Williams, Pediat Res 1:823-826 (1977).
Alcon Inc.
Fay Zohreh A
Schultz Teresa J.
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