Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – In an organic compound
Patent
1995-05-16
1997-11-18
Hollinden, Gary E.
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
In an organic compound
424 141, 424450, 4352401, 4352404, 435243, 4351723, 514 2, 514 44, A61K 5108, C12N 500, A01N 3718
Patent
active
056884885
ABSTRACT:
A method is provided for enhancing transmembrane transport of a diagnostic agent across a membrane of a living cell. The method comprises contacting a membrane of a living cell with a complex formed between said diagnostic agent and ligands selected from biotin or biotin receptor-binding analogs of biotin, folate or folate receptor-binding analogs of folate, riboflavin or riboflavin receptor-binding analogs of riboflavin to initiate receptor mediated transmembrane transport of the ligand complex. The method is used for imaging tissues in vivo.
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Heinstein Peter Frederick
Horn Mark Alan
Low Philip Stewart
Hartley Michael G.
Hollinden Gary E.
Purdue Research Foundation
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