Composition and method for treating nonalcoholic...

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills

Reexamination Certificate

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C424S489000, C424S702000, C514S458000, C514S474000, C514S078000, C514S725000

Reexamination Certificate

active

07018652

ABSTRACT:
Nonalcoholic steatohepatitis (NASH) is a disease of the liver characterized by inflammation and damage to the liver cells. Typically, steatohepatitis involves inflammation of the liver related to fat accumulation, and mimics alcoholic hepatitis but is observed in patients who seldom or never consume alcohol. Nonalcoholic steatohepatitis can lead to serious liver damage, and ultimately cirrhosis. The present invention provides methods and compositions useful for the treatment or alleviation of nonalcoholic steatohepatitis and the pharmaceutical formulations for their administration to a human. Specifically, compositions comprised of lecithin, antioxidants and vitamin B complex are administered parenterally, most preferably by oral administration. Specific therapeutic formulations include admixtures of these compounds and specific dosage formulations include daily oral administrations of these compounds in tablet or powder forms.

REFERENCES:
patent: 4080466 (1978-03-01), Taninaka
patent: 5595982 (1997-01-01), Harless
patent: 5662991 (1997-09-01), Smolik et al.
patent: 6180139 (2001-01-01), Hsia et al.
patent: 98/18491 (1998-05-01), None

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