Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Conjugate or complex
Patent
1989-07-13
1992-07-14
Brown, Johnnie R.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Conjugate or complex
424 48, 424408, 424464, 514813, 131270, A61K 3578, A24F 4700
Patent
active
051301326
DESCRIPTION:
BRIEF SUMMARY
The invention refers to an anti-smoking remedy with biochemical effect. More and more attention is paid to the disturbances of health associated with or caused by smoking. In the meantime it has also become generally known that non-smokers who inhale the smoke of other people's cigarettes have to fear in the long run an impairment of their health. That is why in the last years various methods of medicines against smoking have been presented which aimed to disgust the smoker with smoking, to motivate him psychologically against smoking, to shift the pleasure of smoking to other physical comforts, etc.
The known chemical and biochemical anti-smoking remedies generally have unwanted side effects. Moreover, their efficacy is not always guaranteed. The intake, particularly the prolonged intake of these remedies requires a firm and constant will which, as known by experience, the patient has in the initial phase but often is not able to maintain after a certain period of withdrawal. Especially when the first withdrawal symptoms and side effects, such as weight gain, occur. It is precisely at this moment that the will-power of most of them fails. At this stage the known biochemical remedies do not sufficiently support the patient who is willing to stop smoking.
The objective which underlies this invention is therefore to avoid the detriments of the known biochemical anti-smoking remedies and to present a biochemical remedy which in a relatively short time, for example a few days (2 to 5 days), disgusts the smoker with smoking to such a degree that he will stick to the treatment also for the following days. Already during first days of intake the preparation shall provoke such a strong aversion to smoking that the person who is willing to stop smoking feels physically unwell, in particular nauseous, if he smokes after intake of the preparation or inhales the smoke of other people's cigarettes. The invention aims at producing a strong anti-nicotine effect. A feeling of incompatibility between tobacco products and the invention-conforming preparation is created.
This objective is achieved by anti-smoking remedy with biochemical effect which consists of the following non-toxic plant components: Radix Bupleuri, Radix Peucedani, Rhizoma Cimicifugae and Tubera Pinelliae. To these components can be added: Rhizoma Phragmites or a mixture of Pinellia ternata and Liquiritiae; Robinia pseudo-acacia can substitute for Liquiritiae.
These components can be presented in various galenic forms, for example chewing tablets, normal tablets for oral use, infusion, etc. Preference is given to the chewing tablet. In the form of a chewing tablet, the strong bitter taste of the preparation is fully perceived, but it can be modified or altered by appropriate additives (sugar, aromatics, etc.).
Combined, the mentioned components cause an aversion to smoke and smoking, and this already at the moment a cigarette is lighted up. Aversion is also felt when inhaling the smoke of other people's cigarettes. In both situations, active and passive smoking, the intake of the pharmaceutical preparation produces a bitter taste in the mouth which, first of all, spoils the pleasure of smoking. In addition an effect is produced on the central nervous system in form of a defense reaction which is attributed to a change in the sensation of taste in the brain. Moreover, the parasympathetic nervous system is stimulated provoking sickness and nausea. Sickness resp. nausea are intensified due to the fact that less oxygen is absorbed when inhaling smoke. The invention-conforming herb mixture strengthnes nerves and organs. The anti-smoking effect is already felt after a few days, for example after 2 to 5 days.
The plant components used have a strong anti-nicotine effect and provoke nausea and even vomiting when smoking a cigarette or inhaling the smoke of other people's cigarettes. This is due to a taste incompatibility between tobacco products and the active constituents of the plants.
The intake of the invention-conforming pharmaceutical preparation leads to a
REFERENCES:
patent: 2600700 (1952-06-01), Smith
patent: 3011944 (1961-12-01), Taizo
patent: 4871540 (1989-10-01), Kojima et al.
"Codex Vegetables", Steinmetz, pp. 25, 812, 822 (1957).
"Tobacco Experimental and Clinical Studies", Larson et al. The Williams & Wilkins Co. (1961).
Brown Johnnie R.
Varma A.
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