Composition and method for treating lupus nephritis

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S320100, C435S328000, C536S023500, C530S350000

Reexamination Certificate

active

07491513

ABSTRACT:
The present invention provides novel isolated BFLP0169 polynucleotides and polypeptides encoded by the BFLP0169 polynucleotides. Also provided are the antibodies that immunospecifically bind to a BFLP0169 polypeptide or any derivative (including fusion derivative), variant, mutant or fragment of the BFLP0169 polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the BFLP0169 polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states, as well as to other uses.

REFERENCES:
patent: 6313264 (2001-11-01), Caggiano et al.
patent: 2002/0197679 (2002-12-01), Tang et al.
patent: 2003/0049804 (2003-03-01), Pompejus et al.
patent: 2004/0258678 (2004-12-01), Bodary et al.
Balow, J.E. et al., “ New Prospects for treatment of lupus nephritis,”Semin. Nephrol., 20(1):32-39 (2000).
Davis, J.C. et al., “Lupus nephritis,”Current Opin. Rheumatol., 8(5):415-423 (1996).
Mercada, L. and Deray, G., “Lupus nephritis, review of the current pharmacological treatments,”Expert Opin. Pharmacother., 5(11):2263-2277 (2004).
Rahman, Z.S.M. et al., A novel susceptibility locus on chromosome 2 in the (New Zealand black×New Zealand white) F1hybrid mouse model of systematic lupus erythematosus,J. Immunol., 168(6):3042-3049 (2002).
Tsao, B.P., “Genetic susceptibility to lupus nephritis,”Lupus, 7(9):585:590 (1998).
Ngo, Thomas J. et al.,The Protein Folding Problem and Tertiary Structure Prediction, 1994, 492-494.
Metzler et al.,Nature Structural Biol., 1997, 4:527-531.
Attwood,Science, 2000, 290:471-473.
Skolnick et al.,Trends in Biotech., 2000, 18(1):34-39.
Whisstock et al.,Quarterly reviews of Biophysics, 2003, 36:307-340.
Drake et al., “Genetic analysis of the NZB contribution to lupus-like autoimmune disease in (NZB×NZW) F1 mice,”Pro Natl. Acad. Sci. USA, 91:4062-66, 1994.
Guglielmotti et al., “Bindarit prolongs survival and reduces renal damage of NSB/W lupus mice,”Clin. Exp. Rheumatol., 16:149, 1998.
Finck et al., “Interleukin 6 promotes murine lupus in NZB/NZW F1Mice,”The J. Clin. Invest., 94:585-591, 1994.
Yang et al., “Dietary conjugated linoleic acid protects against end stage disease of systemic lupus erythematosus in the NZB/W F1 mouse,”Immunopharmacol. Immunotoxicol., 22:433-49, 2000.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Composition and method for treating lupus nephritis does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Composition and method for treating lupus nephritis, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Composition and method for treating lupus nephritis will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4056038

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.