Drug – bio-affecting and body treating compositions – Lymphokine – Interleukin
Patent
1992-12-10
1994-04-05
Schain, Howard E.
Drug, bio-affecting and body treating compositions
Lymphokine
Interleukin
424 851, 530351, C07G 700, A61K 3702
Patent
active
053002920
ABSTRACT:
A method for treatment of inflammation, comprising the step of administering to a patient in need thereof an effective, inflammation-inhibiting amount of a composition comprising IL-6, or IL-6 and TGF.beta. together in a weight ratio of from about 5:95 to 95:5, preferably from about 20:80 to 80:20. Also disclosed is a composition for treatment of inflammation, comprising as active ingredients IL-6 and TGF.beta. in a weight ratio of from about 5:95 to about 95:5, optionally comprising a carrier in combination with the active ingredients, and a method of reducing migration of neutrophils into tissue of an animal which has received an inflammatory stimulus, comprising the step of administering to the tissue an effective neutrophil-migration-inhibiting amount of a composition as defined above.
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Schain Howard E.
The Regents of the University of California
Touzeau P. Lynn
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