Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant virus encoding one or more heterologous proteins...
Reexamination Certificate
2007-09-04
2007-09-04
Salimi, Ali R. (Department: 1648)
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant virus encoding one or more heterologous proteins...
C424S229100, C435S320100
Reexamination Certificate
active
10477444
ABSTRACT:
The present invention provides a herpes virus in which a non-essential gene for replication is inactivated More particularly, the present invention provides a herpes virus in which a non-essential gene for replication present in a UL or US region is inactivated. More preferably, the non-essential gene for replication contains US3 or UL56. The herpes virus may be preferably a herpes simplex virus, and more preferably herpes simplex virus 1 or herpes simplex virus 2. The present invention provides a method, composition and use for treating various diseases or disorders including tumor and infectious diseases. The present invention also provides a method, composition and use for activating a prodrug.
REFERENCES:
patent: 5837532 (1998-11-01), Preston et al.
patent: 5922328 (1999-07-01), Spector et al.
patent: 6641817 (2003-11-01), Coffin et al.
patent: WO96/04394 (1996-02-01), None
patent: WO98/42195 (1998-10-01), None
Pyles, R.B. and Thompson, R.L., “Evidence that the Herpes Simplex Virus Type 1 Uracil DNA Glycosylase is Required for Efficient Viral Replication and Latency in the Murine Nervous System”, Journal of Virology, vol. 68, No. 8, Aug. 1994, pp. 4963-4972.
Elrifi, Esq. Ivor R.
M's Science Corporation
Mintz Levin Cohn Ferris Glovsky and Popeo PC
Nishiyama Yukihiro
Salimi Ali R.
LandOfFree
Composition and method for treating cancer using herpes virus does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Composition and method for treating cancer using herpes virus, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Composition and method for treating cancer using herpes virus will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3793929