Composition and method for topical application to skin, hair and

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Cosmetic – antiperspirant – dentifrice

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514847, 424 701, 424 61, A61K 948, A61K 700

Patent

active

058826610

ABSTRACT:
A composition and method thereof treating or conditioning human skin, hair or nails is described. The composition is topically applied in an effective amount and contains from about 0.0001 to about 50 wt. % of a ceramide derivative containing sphingoid bases having amide, but not ester linkages to a 2 (alpha)-hydroxy carboxylic acid and a safe and effective amount of a pharmaceutical or cosmetically acceptable carrier. The composition effectively treats or conditions areas of fine flakes having histogram values of 10 to 128. Treated areas exhibit a desquamation value difference of 1.0 or greater at day 28 after treatment commences compared to a desquamation value of untreated areas.

REFERENCES:
Ceramides Brochure, "Human Skin-identical Ceramides", 1984, by H. Lambers et al., pp. 2-8.

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