Composition and method for the controlled release of metal catio

Details Composition and method for the controlled release of metal catio Composition and method for the controlled release of metal catio

1994-07-25

1998-01-27

Webman, Edward J.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Matrices

424486, 424488, 424499, 424501, 424443, 424444, 424423, 424426, 424434, 424436, A61K 910, A61K 916

Patent

active

057119686

ABSTRACT:
This invention relates to a composition, and method of forming said composition, for the controlled release of interferon. The controlled release composition of this invention comprises a biocompatible polymer and particles of metal cation-stabilized interferon, wherein the particles are dispersed within the biocompatible polymer.
The method of the invention, for producing a composition for the controlled release of interferon, includes dissolving a polymer in a polymer solvent to form a polymer solution, dispersing particles of metal cation stabilized-interferon particles in the polymer solution, and then solidifying the polymer to form a polymeric matrix containing a dispersion of the interferon particles.

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