Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Reexamination Certificate
2000-07-19
2001-10-02
Jarvis, William R (Department: 1614)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
C514S560000, C514S642000
Reexamination Certificate
active
06297280
ABSTRACT:
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to a composition for suppressing behavior problems of pets, and a method for suppressing behavior problems of pets using the same.
2. Discussion of the Related Art
With the popularity of owning a pet and the change of the housing situations of recent years, the method of keeping a pet has been changed. For example, regarding a dog, while it was kept as a watch dog or a hunting dog in the past, it has now been kept indoors as an indoor dog. Similarly, regarding a cat, while it was kept mainly out of the house in the past, it has now been kept mainly indoors. Also, how an owner values a pet has changed: Thinking of a pet as a companion animal that the pet is regarded as a member of family has been infiltrated in the people's mind.
Because of such changes, there arises a new disease, namely behavior problems associated with failure in pet breeding and training for keeping it indoors and also with old age.
For example, regarding the indoor dogs, there have been known to show behaviors such as attack, destruction, inappropriate elimination, licking their paws repeatedly, and excess barking. Also, regarding the cats, there have been known to show behaviors such as inappropriate elimination and scratching.
As a means to suppress these behavior problems, Japanese Patent Laid-Open No. Hei 2-308737 discloses a technique relating to an automatic training device for pets to regulate the behavior automatically such that an animal such as a pet does not go out of a certain area. However, the device has a complicated structure with a defect of complicated operation, and is undesirable from the viewpoint of protecting an animal from harm since a high voltage is applied to a pet which shows abnormal behaviors.
Also, pet owners have been instructed to ignore a dog from about 30 minutes before going out, namely to give no attention for the dog at all, and further to ignore behaviors of the dog such as gladly licking and jumping when the pet owners return home until the dog calms down. However, such a therapeutic method could be easily understood to mean that the pet owner should not have any contact with the dog at all, and when such understanding is made, the symptoms of behavior problems are likely to get rather worse.
Further, there are proposed administration of an anti-anxiety agent, a hormone agent, a tranquilizer, a sedative, an anti-epileptic agent and a pheromone as the pharmacotherapy. However, since there are problems of side effects and stresses of the pet arising from the administration of the pharmaceuticals, these proposals have not yet came into practical use.
Declaw, cutting off the claw of cat, has a problem from the viewpoint of protecting an animal from harm, and therefore is not practiced in most case.
An object of the present invention is to provide a composition for suppressing behavior problems of pets which cannot be effectively solved by the conventional methods, and a method for suppressing behavior problems using it.
The above and other objects of the present invention will be apparent from the following description.
SUMMARY OF THE INVENTION
As a result of intense research in view of suppressing the behavior problems of pets, the present inventors have found that a composition comprising a theanine, and optionally further comprising one or more compounds selected from the group consisting of highly unsaturated fatty acids and cholines can suppress the behavior problems of pets, thereby accomplishing the present invention.
Specifically, the present invention is directed to:
[1] a composition for suppressing behavior problems of pets, comprising theanine;
[2] a method of suppressing behavior problems of pets, comprising administering the composition of item [1] above to a pet having behavior problems; and
[3] use of the composition of item [1] above for suppressing behavior problems of pets.
DETAILED DESCRIPTION OF THE INVENTION
The composition for suppressing behavior problems of pets of the present invention can be used for the purpose of suppressing behavior problems of pets arising from various causes. The desired effects of the composition of the present invention is manifested on the basis of the action of suppressing behavior problems of pets found for the first time for theanine contained in the above composition.
The theanine used in the present invention is a kind of an amino acid, and is a water-soluble white crystalline powder.
Methods for preparing theanine used in the present invention may be any of known methods. Examples thereof include a method of extracting it from tea-leaves; a method of preparing it by an organic synthesis reaction [
Chem. Pharm. Bull.,
19(7), 1301-1307 (1971)]; a method of preparing it by treating a mixture of glutamine and ethylamine with glutaminase (Japanese Examined Patent Publication No. Hei 7-55154); a method comprising culturing culture cells of tea in a medium containing ethylamine, and promoting proliferation of the culture cells, with increasing an dosage of accumulated theanine in the culture cells (Japanese Patent Laid-Open No. Hei 5-123166); and a modification method of one disclosed in Japanese Examined Patent Publication No. Hei 7-55154 and Japanese Patent Laid-Open No. Hei 5-123166 using an ethylamine derivative, such as ethylamine hydrochloride, in place of ethylamine. The term “tea-leaves” as used herein refers to green tea, oolong tea, black tea, and the like. The theanine obtained by the methods described above may be of any of L-form, D-form and DL-form, among which the L-form is preferred in the present invention, because it is approved as a food additive, and it is economically utilizable. In addition, the theanine used in the present invention may be of any forms, such as purified products, crudely purified products, extracts and commercialized products [trade names: “SUNTHEANINE” and “TEAPECUS” commercially available from Taiyo Kagaku Co., Ltd.].
From the viewpoint of enhancing an action of suppressing behavior problems of pets owned by theanine, it is preferable that the composition of the present invention further comprises one or more compounds selected from highly unsaturated fatty acids and cholines. Although the function mechanism is not clarified, the compound can act to enhance the action of suppressing behavior problems owned by theanine. Therefore, the same level of effects as that exhibited with theanine alone can be obtained, with a smaller dosage of theanine required as compared to the case where theanine is used alone by the copresence of the compound.
The term “highly unsaturated fatty acid” in the present invention refers to unsaturated fatty acids having 18 or more carbon atoms such as linoleic acid, &ggr;-linolenic acid, dihomo-&ggr;-linolenic acid, arachidonic acid, &agr;-linolenic acid, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), among which arachidonic acid and DHA are preferable, from the viewpoint of effectively enhancing an action of suppressing behavior problems of pets owned by theanine, and DHA is more preferable.
The supplying form of the highly unsaturated fatty acid used in the composition of the present invention includes, but not particularly limited to, fats and oils containing the fatty acid and purified products of the fatty acid. In addition, for the purpose of stabilizing the fatty acid, the highly unsaturated fatty acid can be used in a combination of a functional protein preparation disclosed in Japanese Patent Laid-Open No. Hei 9-9878, to give powdery fats and oils.
Concrete examples of the forms of the highly unsaturated fatty acid are disclosed, for instance, as follows. When the highly unsaturated fatty acid is DHA, it can be in the form of DHA powdery oils and fats [“Kinoseiyushi no Funmatsu Anteika” (Stabilization by Making Powdery Form of Functional Fats and Oils), “Dai 53 Kai Nihon Eiyo Shokuryo Gakkai Koen Yoshishu” (Summary of 53rd Academic Meeting for Japanese Society of Nutrition
Ishihara Noriyuki
Juneja Lekh Raj
Sakanaka Senji
Shu Seiji
Birch & Stewart Kolasch & Birch, LLP
Jarvis William R
Taiyo Kagaku Co., Ltd.
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