Composition and method for stabilization of dinucleotides

Chemistry: analytical and immunological testing – Composition for standardization – calibration – simulation,... – Preservative – buffer – anticoagulant or diluent

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435188, 436 8, 436 17, G01N 3100, C12N 996

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active

047043652

ABSTRACT:
A reduced dinucleotide, preferably nicotinamide adenine dinucleotide (NADH), is stabilized in an aqueous base liquid containing propylene glycol, boric acid and a buffer capable of buffering within a pH range of 8-11. The stabilized liquid contains greater than 50% (v/v) water. The remaining volume contains propylene glycol which has been chemically treated to remove oxidants. This reagent may be used by itself or in conjunction with an assay reagent system for use in the clinical laboratory.

REFERENCES:
patent: 4153511 (1979-05-01), Modrovich
patent: 4372874 (1983-02-01), Modrovich

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