Composition and method for reducing structural defects

Details Composition and method for reducing structural defects Composition and method for reducing structural defects

1993-11-26

1996-05-14

Fay, Zohreh

Drug, bio-affecting and body treating compositions

Inorganic active ingredient containing

Phosphorus or phosphorus compound

424610, 424663, 424673, 514912, A61K 3343, A61K 3314

Patent

active

055165346

ABSTRACT:
The invention provides a composition and method for reducing structural defects in metastable systems. Structural defects represent spaces or vacancies in the structural order of the metastable system, which can be restored to the predefect order through the use of structure makers. These structure makers will then occupy the space or vacancy of the defect, restoring the order of the system. Lithium ions are used as a preferred structure maker to reduce the structural defects that lead to cataract in a human lens.

REFERENCES:
Schreiber et al. "Lithium Administered by Eye Drops: A Better Treatment . . . " Prog. Neuro-Psychopharmacol. & Biol. Psychiat. 15, 315-321 (1991).
Kobayashi et al. "Effect of 2,6-diiodo-4-nitrophenol and 3,5-diiodosalicylic acid . . . " Atarashii Ganka 4(3), 403-6 (1987).
Iwata et al. "Cations involved in cataract formation. I. The turbidimetric aspect . . . " Nippon Ganka Kiyo 29(6), 855-58 (1978).
Bentley et al. "Effects of Lithium on Ionic Composition and Electrical . . . " Exp. Eye Res. 25, 447-457 (1977).
Farkash et al. "Pupillary Mydriasis Found to be Exerted Through M.sub.3 Muscarinic . . . " Lithium 4, 279-283 (1993).

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