Composition and method for reducing acetaldehyde toxicity

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...

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Details

514474, 514811, A01N 3700, A01N 4308

Patent

active

052023540

ABSTRACT:
A novel composition and method are disclosed for reducing acetaldehyde toxicity, especially for preventing and relieving hangover symptoms in humans. The composition comprises (a) a compound of the formula: ##STR1## wherein R is hydrogen or an acyl group; R' is thiol or sulfonic group; and n is an integer of 1 or 2, (b) ascorbic acid or a salt thereof and (c) a disulfide type thiamine derivative or a salt thereof. The composition is orally administered, preferably in the form of tablets.

REFERENCES:
patent: 2283817 (1942-05-01), Martin et al.
patent: 4496548 (1985-01-01), Moldowan et al.
patent: 4528295 (1985-07-01), Tabakoff
patent: 4593020 (1986-06-01), Guinot
Sprince et al., Agents and Actions, vol. 5/2 (1975), pp. 164-173.

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