Composition and method for radiation synovectomy of arthritic jo

Details Composition and method for radiation synovectomy of arthritic jo Composition and method for radiation synovectomy of arthritic jo

1989-09-15

1991-08-13

Maples, John S.

Glass manufacturing

Processes

Self-supporting particle making

65 3013, 65 31, 424 11, 501 33, 501 55, 501 64, C03B 1910, C03C 1500, C03C 1200

Patent

active

050393260

ABSTRACT:
A method for preparing nonradioactive microspheres adapted for radiation synovectomy of arthritic joints in a mammal involves forming the microspheres by doping a biodegradable glass material which may be lithium or potassium silicate, lithium or potassium aluminosilicate, lithium or potassium aluminoborate, lithium or potassium germanate or lithium or potassium aluminogermanate with an isotope which may be samarium, holmium, erbium, dysprosium, rhemium or yttrium so that the isotope is chemcially dissolved in and distributed uniformly throughout the glass material. The doped glass material is then treated with an acid wash to produce a thin layer on the surface thereof and heat treated to improve the chemical durability of the glass material by rendering the solubility of the layer lower than that of the underlying glass material.

REFERENCES:
patent: 3972721 (1976-08-01), Hammel et al.
patent: 4547233 (1985-10-01), Delzant
patent: 4789501 (1988-12-01), Day et al.

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