Composition and method for radiation synovectomy of arthritic jo

Compositions: ceramic – Ceramic compositions – Glass compositions – compositions containing glass other than...

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501 42, 501 52, 501 55, 501 64, 501 65, 501 68, 424 11, 600 3, C03C 1200, C03C 3095

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050117971

ABSTRACT:
Radioactive microspheres for radiation synovectomy of arthritic joints in a mammal comprises a biodegradable glass material and a beta radiation emitting radioisotope chemically dissolved in and distributed substantially uniformly throughout the glass material. The biodegradable glass material may be lithium silicate, lithium aluminosilicate, lithium aluminoborate, lithium germanate, lithium aluminogermanate, potassium silicate, potassium aluminosilicate, potassium aluminoborate, potassium germanate or potassium aluminogermanate and the beta radiation emitting radioisotope may be samarium-153, holmium-166, erbium-169, dysprosium-165, rhenium-186, rhenium-188 or yttrium-90. Method for preparing such microspheres and for carrying out radiation synovectomy of arthritic joints utilizing such microspheres are also disclosed.

REFERENCES:
patent: 3147225 (1964-09-01), Ryan
patent: 3334050 (1967-08-01), Grotenhuis et al.
patent: 4789501 (1988-12-01), Day et al.

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