Composition and method for producing prolonged pain relief

Details Composition and method for producing prolonged pain relief Composition and method for producing prolonged pain relief

1985-03-11

1986-07-08

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

424 83, 514535, A61K 3124, A61K 31215, A61K 31745

Patent

active

045993548

ABSTRACT:
A composition and method for producing lasting pain relief in a body by injection. The composition consists essentially of a sterile, stable suspension of butyl aminobenzoate in a non-toxic, aqueous carrying medium in which the butyl aminobenzoate is insoluble. The composition is substantially devoid of dextran and contains polyethylene glycol as a suspending agent.

REFERENCES:
patent: 4344965 (1982-08-01), Stone
The Pharmacological Basics of Therapeutics, Louis S. Goodman et al., The MacMillan Company, New York, 1955, p. 370.
Neural Blockade In Clinical Anesthesia and Management of Pain, edited by Michael J. Cousins et al, J. B. Lippincott Company, Philadelphia, 1980, p. 102.
Kenny, "Relief of Pain In Intractable Cancer of The Pelvis", British Medical Journal, Nov. 29, 1947, p. 862.
Teevens, "Relief of Sciatica In Carcinoma of The Prostate by Protocaine", Canad. M. A.J., Apr. 1948, vol. 58, p. 384.
Swerdlow, "Relief of Intractable Pain, Monographs in Anaesthesiology", vol. 1, Excerpta Medica, Amsterdam, London, New York, 1974, p. 169.
Katz et al, "Neuropathology of Neurolytic and Semidestructive Agents," in Neural Blockade in Clinical Anesthesia and Management of Pain, edited by Michael J. Cousins et al, J.B. Lipincott Company, Philadelphia, 1980, p. 128.

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