Composition and method for post-surgical adhesion reduction with

Details Composition and method for post-surgical adhesion reduction with Composition and method for post-surgical adhesion reduction with

1990-08-10

1992-06-30

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424 7837, 424427, 424431, 514944, A61K 9107, A61K 4734, A61K 4736

Patent

active

051261413

ABSTRACT:
A process and compositons for reducing post-surgical adhesion formation/reformation in mammals following injury to organs situated in mammalian body spaces. Aqueous, thermally reversible gel compositions, preferably at mammalian body fluid pH, comprising a polyoxyalkylene polymer and an ionic polysaccharide are applied to injured areas of the organs situated in body cavities such as, the peritoneal, pelvic, or pleural cavity. The aqueous gels are rendered thermally irreversible upon contact with a counter-ion.

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