Composition and method for inhibiting terminal deoxyribonucleoti

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514908, 544312, A61K 31505, C07D23954

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active

045769486

ABSTRACT:
New uracil compounds having the formula: ##STR1## wherein X is C.sub.1 -C.sub.10 alkoxy or amino are provided. These compounds are useful in treating patients having leukemia, the cells of which express terminal deoxynucleootidyl transferase.

REFERENCES:
Wright et al, Journal of Med. Chemistry, vol. 23 (1), (Jan. 1980) pp. 34-38.
Paul et al, Chemical Abstracts, vol. 61, (1964), 5642(g)-5643(a).

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