Composition and method for inhibiting platelet aggregation

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Allergen or component thereof

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549 45, A61K 3138

Patent

active

043047840

ABSTRACT:
This invention relates to a pharmaceutical use of 3-oxo-2,3-dihydro[1]benzothiophene-2-spirocyclopropane. The compound exhibits strong inhibition activity of thrombocyte aggregation in mammalian blood. The compound and its pharmaceutical composition are useful for the prophylaxis or treatment of cardiovascular disturbance such as thrombosis.

REFERENCES:
patent: 4089970 (1978-05-01), Beg
Okitsu et al., Heterocycles, 6(11) pp. 1877-1880 (1977).
Cussac et al., Annalis Pharmaceutiques Francaisis, 1975, No. 10, pp. 513-529.

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