Drug – bio-affecting and body treating compositions – Dentifrices – Fluorine or fluorine compound containing
Patent
1977-12-29
1979-10-09
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Dentifrices
Fluorine or fluorine compound containing
A61K 718
Patent
active
041706366
ABSTRACT:
A dentifrice composition is provided which contains a compound having the formula (R.sub.f).sub.m YX wherein R.sub.f is a fluoroaliphatic radical having from about 4 to 16 carbon atoms; Y is a calcium-complexing moiety; X is a terminal group which does not interfere with the complexing ability of said calcium-complexing moiety; and m is an integer of at least one. A method of inhibiting plaque formation in an oral environment is also provided.
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March Advanced Organic Chemistry : Reactions, Mechanisms and Structures, pp. 324, 368, McGraw-Hill, (1968).
Chang Robert W. H.
Engel Michael R.
LaFleur Linda L.
Alexander Cruzan
Lilly James V.
Minnesota Mining and Manufacturing Company
Rose Shep K.
Sell Donald M.
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