Composition and method for inhibiting perspiration with S-substi

Details Composition and method for inhibiting perspiration with S-substi Composition and method for inhibiting perspiration with S-substi

1973-03-29

1976-04-27

Ore, Dale R.

Drug, bio-affecting and body treating compositions

Anti-perspirants or perspiration deodorants

A61K 732

Patent

active

039535908

ABSTRACT:
A method for inhibiting perspiration comprises applying to a site at which perspiration is normally exuded, an antiperspirant of the formula ##SPC1##
Or a salt thereof. In preferred compounds, A, B, D, E, and G are hydrogen and R is phenyl, alkyl, hydroxyalkyl, aminoalkyl, alkenyl or oxopyridyl. Also useful are the corresponding hydrohalic acid salts. The compounds are preferably applied to the human axillae as aqueous antiperspirant compositions containing a surface active agent. Some of the S-substituted benzothiohydroximic acids and hydrohalic acid salts are new compounds of especially good antiperspirant activities, e.g., those in which the R group is linear alkyl of 6 to 9 carbon atoms, lower aminoalkyl, lower hydroxyalkyl, 1-oxopyridyl, and the hydrochloric acid salts of the compounds in which R is lower aminoalkyl.

REFERENCES:
patent: 2786865 (1957-03-01), Copenhaver
patent: 3374260 (1968-03-01), Buchanan

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