Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2006-07-11
2006-07-11
Gupta, Anish (Department: 1654)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C424S093200, C424S093210, C435S375000, C530S399000
Reexamination Certificate
active
07074762
ABSTRACT:
A method and composition for enhancing the development of metanephric tissue upon transplantation into an allogenic or xenogenic host are disclosed. Metanephric tissue is removed from an embryonic donor and is contacted with a composition comprising one or more growth factors for metanephric development. The composition can be administered to the metanephric tissue in vitro prior to implantation of the donor tissue in the transplant recipient, or can be administered in vivo either during or subsequent to the transplantation procedure.
REFERENCES:
patent: 5106832 (1992-04-01), Froesch
patent: 5135915 (1992-08-01), Czarniecki et al.
patent: 5273961 (1993-12-01), Clark
patent: 5728676 (1998-03-01), Halloran
patent: 5744304 (1998-04-01), Munford
patent: 5759830 (1998-06-01), Vacanti et al.
patent: 5770417 (1998-06-01), Vacanti et al.
patent: 5976524 (1999-11-01), Hammerman
patent: 0 853 942 (1998-07-01), None
patent: 97/49798 (1997-12-01), None
patent: WO97/49798 (1997-12-01), None
patent: 98/50061 (1998-11-01), None
Chiang et al., Human Placental Lactogen Inhibits Growth Without Changing Serum Lenils of IGF-I in Rats, Acta Endocrinologica, 127 (2) 147-51 (Abs.), Aug. 1992.
File Cpalus on STN. AN No. 1992:249442. Rogers et al. “Metanephric transforming growth factor-.alpha.-is required for renal organogenesis in vitro.” Am. J. Physiol. vol. 262 (4, pt. 2) pp. F533-G539. Abstract only. 1992.
File Medline on STN AN No. 91094244. Woolfe et al. “Creation of a functional chimeric mammalian kidney.” Kidney International, vol. 38, No. 5, pp. 991-997. Abstract only. Nov. 1990.
Chemical Abstracts. Liu et al. Abstract No. 122:179195e. p. 205. vol. 122, No. 15.
Rogers et al. Metanephric Transforming Growth Factor Alpha is Required for Renal Organogenesis in Vitro', American J. of Physiol. vol. 262, No. 4, ot, 2. pp. F533-F539. 1992.
Liu et al. “Trophic effect of insulin-like growth factor-I on metanephric development: Relationship to proteoglycans” Eur. J. Cell. Biol. vol. 65, No. 2, pp. 378-391. 1994.
Woolf, MD, A.S., et al., “Integration of New Embryonic Nephrons Into the Kidney”,Amer. Jour. of Kidney Diseases, vol. XVII, 6:611-614 (Jun. 1991).
Woolf, A.S., et al., “Creation of a functioning chimeric mammalian kidney”,Kidney Intl.., vol. 38:991-997 (1990).
Churchill, M., “Kidney Transplants in Cyclosporine-Treated Sprague-Dawley Rats”,Transplantation, vol. 49, No. 1:8-13 (Jan. 1990).
Robert, B., “Evidence that embryonic kidney cells expressing flk-1 are intrinsic, vasculogenic angioblasts”,Amer. Physiol. Soc., pp. F744-753 (1996).
Abrahamson, D.R., et al., “Glomerular Development Intraocular and Intrarenal Grafts of Fetal Kidneys”,Lab. Investigation, vol. 64, No. 5:629-639 (1991).
Barakat, T.I., et al., “The capacity of fetal and neonatal renal tissues to regenerate and differentiate in a heterotopic allogeneic subcutaneous tissue site in the rat”,J. Anat., 110; 3:393-407 (1971).
Cooper, D.K.C., et al., “The Pig as Potential Organ Donor for Man”,Springer-Verlag; Xenotransplantation; pp. 481-500 (1991).
Somerville, C.A., et al., “Future directions in transplantation: Xenotransplantation”,Kidney Intl.., vol. 44; Suppl. 42:S-122-S-121 (1993).
Armstrong et al., “Embryonic Kidney Rudiments Grown in Adult Mice Fail to Mimic the Wilms' Phenotype, but Show Strain Specific Morphogenesis,” Experimental Nephrology, 1(3):168-174 (1993).
Tisinai et al., “Comparison of Growth, Neovasculatization and Enzymatic Function of Fetal Intestinal Grafts in the Omentum and Renal Capsule,” J. of Pediatric Surgery, 25(8):914-916 (1990).
Koseki et al., “Integration of Embryonic Nephrogenic Cells Carrying a Reporter Gene into Functioning Nephrons,” American Journal of Physiology, 261(3.1):C550-C554 (1991).
Woolf et al., “Origin of Glomerular Capillaries: Is the Verdict In?” Experimental Nephrology, 6(1):17-21 (1998).
Ferrari et al., “Basic Fibroblast Growth Factor Promotes the Survival and Development of Mesencephalic Neurons in Culture,” Developmental Biology, 133:140-147 (1989).
Rogers, S.A., et al., “Insulin-like Growth Factors I and II are Produced in the Metanephros and are Required for Growth and Development In Vitro”,The Jour. of Cell Biol., vol. 113, No. 6:1447-1453 (Jun. 1991).
Simpson, M., “Immunosuppression in Xenotransplantation”,Xenograft 25; pp. 273-284 (1989).
Rogers, et al., “Transplantation of Developing Metanephroi into Adult Rats,” Kidney International, 54:27-37 (1998).
Hammerman, M.R., “Growth factors in renal development,”Seminars in Nephrology15(4):291-299 (1995).
Antes, L.M., et al., “A serum-free in vitro model of renal microvessel development,”Am. J. Physiol., 274 (Renal Physiol. 43): F1150-F1160, 1998.
Hammerman Marc R.
Rogers Sharon A.
Gupta Anish
Trecartin Richard F.
Washington University
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