Composition and method for improvement of the appearance of scar

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Conjugate or complex

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A01N 6500

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active

058855815

ABSTRACT:
A dermatological composition for use in improving the appearance of scars comprising 20-30 parts by weight of polyethylene glycol 200, 0.005-0.03 parts by weight of preservative, 0.05-0.2 parts by weight of sorbic acid, 0.5-2 parts by weight of allantoin, 1-3 parts by weight of xanthan gum, 5-15 parts by weight of fluid onion extract (Extract Allium Cepa), dermatologically-acceptable aqueous carrier 55-65 parts by weight, perfume oil optional, for a total of 100 parts by weight, in the form of a light milky gel, and a method of improving the appearance of a scar comprising the step of applying to the scar a dermatologically-effective amount thereof.

REFERENCES:
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patent: 4482537 (1984-11-01), El-Menshawy et al.
patent: 5009890 (1991-04-01), DiPippo
patent: 5552162 (1996-09-01), Lee
Lawless "The Illustrated Encyclopedia of Essential Oils," (1995) (Element Books, LTD: London) pp. 78-79, 1995.
Maragakis et al. "Possibilities of scar treatment after thoracic surgery" Drugs Under Experimental and Clinical Research (1995) 21(5): 199-206, 1995.
The Merck Index, Twelfth Edition, 255, p. 48 (1996) and 6980, p. 1174 (1996).
Marla Chadzynska et al., "Contractubex in the Treatment of Burn-Induced Hypertrophic, Keloidal Scars in Children", Der Deutsche Dermatologe 1989, 37 11: 1-4 (1989).
Published by Merz Pharma: Frankfurt (1995).
Allium cepa L.: Chemistry, Analysis and Pharmacology By: Breu, W., Dorsch, W. In: Economic and medical plant research 6: 115-147 (1994).

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