Composition and method for enhancing permeability of topical dru

Details Composition and method for enhancing permeability of topical dru Composition and method for enhancing permeability of topical dru

1988-09-22

1990-01-09

Kight, John

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Web, sheet or filament bases; compositions of bandages; or...

514554, 514560, A61K 906, A61K 922

Patent

active

048927376

ABSTRACT:
A composition and method for enhancing permeability of topical drugs wherein the agent which enhances the permeability of the drug is selected from the group consisting of (1) a choline ester having the formula:

REFERENCES:
patent: 4304765 (1981-12-01), Shell et al.
patent: 4460562 (1984-07-01), Keith et al.
patent: 4777039 (1988-10-01), Lang et al.
Cooper, "Increased Skin Permeability for Lipophilic Molecules", Journal of Pharmaceutical Sciences, vol. 73, No. 8. Aug. 1984, pp. 1153-1156.
Cooper et al., CA:103:59235d "Effect of Fatty Acids and Alcohols on the Penetration of Acyclovir Across Human Skin In Vitro".
Wickett et al., CA:96:187298a, "Penetrating Topical Pharmaceutical Compositions".

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