Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Amino acid sequence disclosed in whole or in part; or...
Reexamination Certificate
2003-03-06
2008-10-21
Campell, Bruce (Department: 1648)
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Amino acid sequence disclosed in whole or in part; or...
C424S192100, C424S261100, C424S236100, C424S093100, C435S069100
Reexamination Certificate
active
07438914
ABSTRACT:
A composition and method for enhancing immune response in a living organism is disclosed. In particular, the present disclosure provides an adjuvant peptide for use in raising an immune response to an antigen. The adjuvant peptide is selected from a group of peptides with an HIV-related sequence. Additionally, the adjuvant peptide can comprise a fusion-protein that acts as a mucosal adjuvant. The adjuvant peptide can be transformed into one or more living cells, such that the mucosal adjuvant can be produced in living cells and then administered by systemic, mucosal or epidermal delivery.
REFERENCES:
patent: 6258782 (2001-07-01), Barney et al.
patent: 6271198 (2001-08-01), Braisted et al.
Coeffier et al. Vaccine 2001, vol. 19, pp. 684-693.
Durrani et al. J. Immunol. Methods 1998, vol. 93, pp. 93-103.
Backstrom, M. et al., “Insertion of a HIV-1 Neutralizing epitope in a surface-exposed internal region of the cholera B-subunit”, Gene, 149: 211-217, 1994.
Backstrom, M., Characterization of an internal permissive site in the choleral toxin B-subunit and insertion of epitopes infection and immunity gene, 165: 163-171, 1995.
George-Chandy et al., “A. Cholera Toxin B. Subunit as a Carrier Molecule Promotes Antigen and Increases..”. Infection and Immunity, 69(9): 5716-5725, 2001.
Arntzen Charles J.
Matoba Nobuyuki
Mor Tsafrir S.
Arizona Board of Regents, Acting for and on Behalf of Arizona St
Campell Bruce
Fulbright & Jaworski L.L.P.
Li Bao Qun
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