Composition and method for detecting HIV with baculovirus derive

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage

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435 71, 435 79, 435 791, 435 792, 435 14, 435 27, 435974, 436501, 436829, C12Q 170

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057891524

ABSTRACT:
The present invention encompasses membranous baculovirus-derived vesicle compositions having exposed on their external surfaces a ligator capable of selectively binding a ligand to be detected. The compositions also have exposed on their outer surfaces a signal reagent capable of reacting with another signal reagent to generate a signal capable of being detected. The present invention also encompasses assay methods for determining the presence and amount of a ligand in a sample using the membranous vesicle compositions of the present invention.

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