Drug – bio-affecting and body treating compositions – Effervescent or pressurized fluid containing – Organic pressurized fluid
Patent
1990-06-08
1991-10-01
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Effervescent or pressurized fluid containing
Organic pressurized fluid
424450, 264 41, 264 44, A61L 904, A61K 3722, B01J 1302
Patent
active
050532170
ABSTRACT:
Pro-liposome compositions comprise membrane lipids such as lecithin or distearyl dimethylammonium chloride, water-miscible solvents such as ethanol, optionally a minor proportion of water, and optionally fatty acid esters and drugs. In addition to excess water they spontaneously form dispersions of liposomes having high void volumes and high drug entrapment ratios. Aerosol compositions are presented in a volatile liquid propellant. On being sprayed they form an aerosol of droplets which, on contact with aqueous media, spontaneously form liposome dispersions.
REFERENCES:
patent: 4590060 (1986-05-01), Ehrenfeld
Chemical abstracts 105:12154c (1986).
Chemical abstracts 103:27787f (1985).
Chemical abstracts 103:156792v (1985).
Kishore G. S.
Page Thurman K.
Phares Pharmaceutical Research NV
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