Composition and column used in HPLC

Details Composition and column used in HPLC Composition and column used in HPLC

1997-08-11

1999-11-30

Therkorn, Ernest G.

Liquid purification or separation

With means to add treating material

Chromatography

2105021, 210635, 210656, 502401, B01D 1508

Patent

active

059936533

ABSTRACT:
An alkyl-phenyl bonded a stationary phase for use in reversed-phase liquid chromatography, having five to ten carbon atoms in the alkyl group, is disclosed. The alkyl-phenyl bonded phase has its unique selectivity, and it is chemically stable in both acidic and basic environments as well as having high retention capacity, hence high resolution. A method for preparing the alkyl-phenyl bonded phase and a column inside of which the alkyl-phenyl bonded phase is packed with are also disclosed. Additionally, a method for performing liquid chromatography and a mixed stationary phase which has more than one alkyl-phenyl phases are disclosed.

REFERENCES:
patent: 3960720 (1976-06-01), Porath
patent: 4544499 (1985-10-01), Tran
patent: 4867884 (1989-09-01), Rendleman
patent: 5011608 (1991-04-01), Damjanovic
patent: 5252216 (1993-10-01), Folena-Wasserman
patent: 5429746 (1995-07-01), Shadle
patent: 5431807 (1995-07-01), Frechet
Mikes' Laboratory Handbook of Chromatographic and Allied Methods, John Wiley & Sons, 1979, New York, p. 157.
Snyder, Introduction to Modern Liquid Chromatography, John Wiley & Sons, 1979, New York, p. 275.

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