Composite polymeric material for biological and medical applicat

Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – Processes of preparing a desired or intentional composition...

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524498, 525 541, 525937, 2601237, 523105, 523106, 523113, C07G 700, C08L 8906, C02C 704

Patent

active

045634904

ABSTRACT:
The invention relates to a composite polymeric material suitable for biological and medical applications and to the method for preparation thereof. The composite material consists of 1-99 wt. % of hydrophilic polymer or copolymer based on methacrylic or acrylic esters, 1-99 wt. % of fibrillar collagen, and up to 2.5 wt. % of a crosslinking agent, based on both polymeric components. The composite material may further comprise biologically active compounds and other auxiliary materials, as fillers and/or plasticizers. The composite material is prepared by dispersing the fibrillar collagen in a solution or a highly swollen dispersion of the synthetic hydrophilic polymer or copolymer in a lytropic agent and the subsequent removal of the lyotropic agent, thus forming a matrix of the synthetic polymer or copolymer penetrated by fibrillar collagen or vice versa. The composite material may be applied on a solid support or reinforced with glass, plastics, cellulose, or metallic materials.

REFERENCES:
patent: 4264155 (1981-04-01), Miyata
patent: 4268131 (1981-05-01), Miyata et al.
patent: 4388428 (1983-06-01), Kuzma et al.

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