Composite nerve guidance channels

Details Composite nerve guidance channels Composite nerve guidance channels

1988-11-18

1991-04-30

Pellegrino, Stephen C.

Surgery

Instruments

Surgical mesh, connector, clip, clamp or band

623 1, 623 12, A61B 1700, A61F 204

Patent

active

050114867

ABSTRACT:
Medical devices and methods employing biocompatible polymers and nerve growth-enhancing active factors are disclosed for use as guidance channels for regenerating nerves. The devices are formed from a porous, tubular membrane containing active factor incorporated within the membrane and having openings adapted to receive the ends of the severed nerve. In one aspect of the invention, the membrane has an impermeable, outer membrane surface and a porous, inner membrane surface through which the active factor can diffuse and which defines the boundary of a lumen through which said nerve may regenerate. Methods for fabricating such devices are also disclosed.

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