Stock material or miscellaneous articles – Coated or structually defined flake – particle – cell – strand,... – Rod – strand – filament or fiber
Patent
1995-06-05
1998-02-24
Ryan, Patrick
Stock material or miscellaneous articles
Coated or structually defined flake, particle, cell, strand,...
Rod, strand, filament or fiber
4283004, 428357, 428361, 428373, 428374, 4284111, 623 11, 623 16, 501 35, 501 55, 501 63, 501 68, C04B 3324, C03C 3076, B32B 1704
Patent
active
057210497
ABSTRACT:
Composite materials formed from bone bioactive glass or ceramic fibers and structural fibers are disclosed. In preferred embodiments, a braid or mesh of interwoven bone bioactive glass or ceramic fibers and structural fibers is impregnated with a polymeric material to provide a composite of suitable biocompatibility and structural integrity. Most preferably, the mesh or braid is designed so that the bioactive fibers are concentrated at the surface of the implant to create a surface comprised of at least 30% bioactive material, thereby providing enhanced bone ingrowth. The interweaving between the bone bioactive glass or ceramic fibers and the core of structural fibers overcomes the problems found in prior composite systems where the bioactive material delaminates from the polymer. Preferred bioactive materials include calcium phosphate ceramics and preferred structural fibers include carbon fibers. Further preferred bioactive materials include aluminum oxide at greater than 0.2%, by mole. Improved prosthetic implants and methods of affixing an implant are thus also disclosed.
REFERENCES:
patent: 4131597 (1978-12-01), Bluethgen
patent: 4202055 (1980-05-01), Reiner et al.
patent: 4239113 (1980-12-01), Gross et al.
patent: 4329743 (1982-05-01), Alexander et al.
patent: 4411027 (1983-10-01), Alexander et al.
patent: 4604097 (1986-08-01), Graves, Jr. et al.
patent: 4781183 (1988-11-01), Casey et al.
P. Boone, et al., "Bone Attachment of HA Coated Polymers," J. Biomed. Mater. Res. 23, No. A2:183-199 (1989).
Gross et al., "The Response of Bone to Surface-Active Glasses/Glass-Ceramics", CRC Critical Reviews in Biocompatibility, 4, 155-179 (1988).
L. Hench, et al., "Bonding Mechanisms at the Interface of Ceramic Prosthetic Materials," J. Biomed. Mater. Res., 2:117-141 (1971).
Hench, L.L., "Bioactive Glasses and Glass-Ceramics: A Perspective", Handbook of Bioactive Ceramics, vol. I, T. Yamamuro, L.L. Hench, and J. Wilson, eds., pp. 7-23, CRC Press, Boca Raton (1990).
F.K. Ko, "Preform Fiber Architecture for Ceramic Matrix Composites," Bull. Am. Cer. Soc. (Feb. 1989).
Kokubo et al., "Chemical reaction of bioactive glass and glass-ceramics with a simulated body fluid", J. Materials Science: Materials in Medicine 3, 79-83 (1992).
Kokubo, K., et al. "Apatite Formation on Ceramics, Metals and Polymers Induced by a CaO SiO.sub.2 Based Glass in a Simulated Body Fluid", Bioceramics, 4, 114-120 (1991).
G. Maistrelli, et al., "Hydroxyapatite Coating on Carbon Composite Hip Implants in Dogs," J. Bone Jt. Surg., 74-B:452-456 (1992).
U. Pazzaglia, et al., "Study of the Osteoconductive Properties of Bioactive Glass Fibers," J. Biomed. Mater. Res. 23, 1289-1297 (1989).
Spector, et al., "Porous Polymers for Biological Fixation," Clin. Ortho. Rel. Res. 235, 207-218 (1988).
H. Tagai, et al., "Preparation of Apatite Glass Fiber for Application as Biomaterials," Ceramics in Surgery, Vincenzini, P. (Ed.), Amsterdam, Elsevier Sci. Pub. Co. (1983), p. 387.
Van Hove et al., Bioceramics, vol. 6, P. Ducheyne and D. Christiansen, eds., pp. 319-325, Butterworth-Heinemann, Oxford (1993).
M. Zimmerman, et al., "The Attachment of Hydroxyapatite Coated Polysulfone to Bone," J. Appl. Biomat. 1, 295-305 (1990).
Ducheyne Paul
Ko Frank
LaCourse William
Marcolongo Michele S.
Ryan Patrick
Trustees of the University of Pennsylvania
Weisberger Rich
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