Composite body for long-term delivery of effective substances

Details Composite body for long-term delivery of effective substances Composite body for long-term delivery of effective substances

1983-04-20

1985-06-25

Van Balen, William J.

Drug, bio-affecting and body treating compositions

Identification or warning feature

Taste or smell or chemical irritation to the eye, nose, or...

424 19, 424 21, 424 35, 4283155, 604890, 604892, A61J 300, A61K 900

Patent

active

045253404

ABSTRACT:
A composite body for long-term delivery of effective substances has a carrier for effective substances composed of a microporous polymer, and a coating composed of cellulose nitrate. The carrier can be composed of a thermoplastic polymer with a substantially isotropic microporous cellular polymer structure with a plurality of substantially spherical cells of a mean diameter between 0.5 and 100 micrometers. The cells are connected with one another by pores. The composite body serves for long-term delivery of peptides, hormones, neurotransmitters, particularly vasopressin and oxytocin.

REFERENCES:
patent: 3985298 (1976-10-01), Nichols
patent: 4164560 (1979-08-01), Folkman et al.
patent: 4235236 (1980-11-01), Theeuwes
patent: 4309996 (1982-01-01), Theeuwes
patent: 4357312 (1982-11-01), Hsieh et al.
patent: 4391797 (1983-07-01), Folkman et al.
patent: 4449983 (1984-05-01), Cortese et al.
patent: 4450198 (1984-05-01), Michaels

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