Complexing of medicinal substances with high-molecular...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C514S060000, C536S111000

Reexamination Certificate

active

07932377

ABSTRACT:
A molecular complex of a high molecular weight carrier substance and of a medicinal substance. The carrier substance has functional groups whereby the carrier substance and the medicinal substance are bound non-covalently. The medicinal substance is insoluble or slightly soluble in water and the carrier substance is readily soluble in water. The carrier substance can be starch or a starch derivative and can have only one functional group for non-covalent binding of the medicinal substance in each molecule.

REFERENCES:
patent: 2661349 (1953-12-01), Caldwell et al.
patent: 3455838 (1969-07-01), Szymanski et al.
patent: 3892867 (1975-07-01), Schoonman
patent: 5260050 (1993-11-01), Ranney
patent: 5424419 (1995-06-01), Hasegawa et al.
patent: 5612203 (1997-03-01), Maruo et al.
patent: 6132787 (2000-10-01), Bunger et al.
patent: 1 106 186 (2001-06-01), None
patent: WO 97/33552 (1997-09-01), None
patent: WO 97/38727 (1997-10-01), None
patent: WO 98/01158 (1998-01-01), None
patent: WO 99/51284 (1999-10-01), None
patent: WO 02/02146 (2002-01-01), None
patent: WO 02/080979 (2002-10-01), None
patent: WO 03/00738 (2003-01-01), None
patent: WO 03/074088 (2003-09-01), None
2006 Chemical Abstracts Catalog, published by Chemical Abstracts Service, p. 52.
Kayser, O. et al., “Formulation and Biopharmaceutical Issues in the Development of Drug Delivery Systems for Antiparasitic Drugs,”Parasitol Res, 90:S63-S70 (2003).
Chowdary, K.P.R., et al., “Biopharmaceutical Studies on Solid Dispersions of Nalidixic Acid in Modified Starches,”Drug Development and Industrial Pharmacy, 20(19): 3015-3022 (1994).
Chiou, W.L., et al., “Pharmaceutical Applications of Solid Dispersion Systems,”J. Pharm. Sci., 60(9): 1281-1302, (Sep. 1971).
Kushida, I., et al., “Improvement of Dissolution and Oral Absorption of ER-34122, A Poorly Water-Soluble Dual 5-Lipoxygenase/Cyclooxygenase Inhibitor with Anti-Inflammatory Activity by Preparing Solid Dispersion,”J. Pharm. Sci., 91(1): 258-266, (Jan. 2002).
Jung, J.Y., et al., “Enhanced Solubility and Dissolution Rate of Itraconazole by a Solid Dispersion Technique,”International Journal of Pharmaceutics, 187:209-218 (1999).
Milby, K.H. et al., “Ion-Exchange Chromatography of Proteins the Effect of Neutral Polymers in the Mobile Phase,” Journal of Chromatography, 482:133-144 (1989).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Complexing of medicinal substances with high-molecular... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Complexing of medicinal substances with high-molecular..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Complexing of medicinal substances with high-molecular... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2639768

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.