Complexing cresolase with copper chelating agents

Details Complexing cresolase with copper chelating agents Complexing cresolase with copper chelating agents

1974-07-26

1976-09-28

Naff, David M.

Textiles: fiber preparation

195 68, 424 94, 424DIG6, C07G 702

Patent

active

039829995

ABSTRACT:
Complexes of Cresolase and copper chelating agents are used for inhibiting L1210 mouse leukemia. Particularly effective complexes are the chelates of cresolase with 8-hydroxyquinoline, .alpha.,.alpha. dipyridyl, and hydroquinone. Tyrosinase obtained from the brown (Type I) common edible mushroom is a suitable source of cresolase. The cresolase active tyrosinase may then be reacted with copper chelating agent to produce the complex.

REFERENCES:
patent: 2956929 (1960-10-01), Cohen et al.
patent: 2958632 (1960-11-01), Schwarz et al.
patent: 3413198 (1968-11-01), Deutsch
hawley, G. G., The Condensed Chemical Dictionary, Van Nostrand Reinhold Co., N.Y., 1971 (p. 457).
Dawson, et al., Plant Tyrosinase (Polyphenol Oxidase), Methods in Enzymology, Academic Press Inc., N.Y., vol. II, 1955, (pp. 817-819).

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