Complexes of Technetium 99m with propylene amine oximes

Details Complexes of Technetium 99m with propylene amine oximes Complexes of Technetium 99m with propylene amine oximes

1987-11-18

1989-04-04

Terapane, John F.

Organic compounds -- part of the class 532-570 series

Organic compounds

Radioactive metal containing

424 11, 564253, A61K 4902, C07C13100, C07D29512, C07F 1300

Patent

active

048188131

ABSTRACT:
Novel propylene amine oxime ligands have the formula ##STR1## where each of R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7 or R.sub.8 may be hydrogen, hydrocarbon, carboxyl, amine, amide or nitrile, provided that, if R.sub.1 is the same as R.sub.9 and R.sub.2 is the same as R.sub.7, then R.sub.8 is not H. These unsymmetrical ligands form complexes with Technetium-99m which are capable, on injection into mammals, of crossing the blood-brain barrier and of being retained in the brain for a time to permit diagnosis.

REFERENCES:
patent: 4374821 (1983-02-01), Glavan et al.
patent: 4444690 (1984-04-01), Fritzberg
patent: 4605758 (1986-08-01), Schloemer
patent: 4615876 (1986-10-01), Troutner et al.

Affiliated with

Also associated with

Rating

Complexes of Technetium 99m with propylene amine oximes does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Complexes of Technetium 99m with propylene amine oximes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Complexes of Technetium 99m with propylene amine oximes will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-180995