Complexes of saponins and their aglycons with phospholipids and

Details Complexes of saponins and their aglycons with phospholipids and Complexes of saponins and their aglycons with phospholipids and

1991-01-18

1992-11-24

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 33, 514 35, 514887, 536 5, 536 171, 536 181, 536 182, 536 551, 536117, 424450, 424401, 554 80, 554224, A61K 31665, A61K 31705, A61K 9127

Patent

active

051661390

ABSTRACT:
Complexes of saponins from Centella asiatica, terminalia sp. and Terminalia sericea and relevant aglycons with phospholipids are described. The saponins may be asiaticoside, madecassicoside and sericoside. The molar ratio of phospholipids to saponins is from 0.5 to 2. The phospholipids are selected from the group consisting of soy lecithins, phospholipids from bovine or swine brain or cutis, phosphatidylcholine, phosphatidylserine, phosphatidylethanolamine in which the acyl groups can be the same or different and are mostly derived from palmitic, stearic, oleic, linoleic, linolenic acids. Pharmaceutical compositions and the method of treatment are also described.

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