Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Reduced antigenicity – reduced ability to bind complement – or...
Patent
1975-04-01
1977-02-22
Gotts, Lewis
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Reduced antigenicity, reduced ability to bind complement, or...
2601125R, A61K 3700, C07C10352
Patent
active
040092640
ABSTRACT:
A complex of a polysaccharide or its derivative with reduced glutathione having in its infrared absorption spectrum no absorption peak at about 2500 cm.sup.-.sup.1 which appears in the infrared absorption spectrum of the reduced glutathione. The complex is prepared by reacting the polysaccharide or its derivative activated with an activating agent selected from cyanogen halides, organic cyanic acid esters and alkyl esters of halogenocarbonic acids, with the reduced glutathione at a pH of less than 7. The complex is especially useful for stabilizing thiol groups.
REFERENCES:
patent: 3619371 (1971-11-01), Crook et al.
patent: 3645852 (1972-02-01), Axen et al.
patent: 3679653 (1972-07-01), Schuck et al.
patent: 3788948 (1974-01-01), Kagedal et al.
patent: 3882097 (1975-05-01), Pfister et al.
Kagedal et al.: Acta Chem. Scan., 25, 1855-1859 (1971).
Dan: Chem. Abst. 68:20005n (1968).
Gotts Lewis
Meito Sangyo Kabushiki Kaisha
Suyat Reginald J.
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