Complexes comprising a prion protein and a peptidyl prolyl...

Details Complexes comprising a prion protein and a peptidyl prolyl... Complexes comprising a prion protein and a peptidyl prolyl...

2006-08-22

2006-08-22

Carlson, Karen Cochrane (Department: 1653)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C435S183000, C435S320100, C530S350000

Reexamination Certificate

active

07094757

ABSTRACT:
The present invention relates to the diagnosis of transmissible spongiform encephalopathies (TSEs). It especially teaches the production of a soluble prion protein (PrP)-chaperone complex and the advantageous use of such chaperone-PrP complex, especially in the detection of PrP in an immunoassay, as well as its use as and immunogen.

REFERENCES:
patent: 4735896 (1988-04-01), Wang et al.
patent: 4879212 (1989-11-01), Wang et al.
patent: 4945042 (1990-07-01), Geiger et al.
patent: 5908626 (1999-06-01), Chang et al.
patent: 5942252 (1999-08-01), Tice et al.
patent: 6207420 (2001-03-01), Harrison et al.
patent: 6316405 (2001-11-01), Rich et al.
patent: 597884 (1986-04-01), None
patent: 0 061 888 (1982-10-01), None
patent: 0 293 249 (1992-08-01), None
patent: 0 280 211 (1994-11-01), None
patent: 0 396 559 (1996-08-01), None
patent: 1 077 262 (2001-02-01), None
patent: WO 92/22573 (1992-12-01), None
patent: WO 93/21346 (1993-10-01), None
patent: WO 93/25533 (1993-12-01), None
patent: WO 94/08012 (1994-04-01), None
patent: WO 97/10253 (1997-03-01), None
patent: WO 98/01349 (1998-01-01), None
patent: WO 98/13496 (1998-01-01), None
patent: WO 00/20606 (2000-04-01), None
patent: WO 00/26251 (2000-05-01), None
patent: WO 00/28011 (2000-05-01), None
Stockton et al. Nov. 11, 2003; Biochemistry 42:12821-12834.
Aslam, M. and Dent, A., The preparation of protein-protein conjugates in “Bioconjugation”, eds. M. Aslam and A. Dent, McMillan Reference, London (1998), pp. 216-363.
Bardwell, J.,Building Bridges: Disulphide Bond Formation in the Cell, Molecular Microbiology (1994) 14(2), 199-205.
Beissinger, M., et al.,How Chaperones Fold Proteins, Biol. Chem., vol. 379, pp. 245-259, Mar. 1998.
Bothmann, H., et al.,The Periplasmic Escherichia coli Peptidylprolyl cis,trans-Isomerase FkpA, The Journal of Biological Chemistry, vol. 275, No. 22, Issue of Jun. 2, pp. 17100-17105, 2000.
Braden, B.C., and Poljak, R.J., Faseb J. 9 (1995) 9-16.
Buchner, J.,Supervising The Fold: Functional Principles of Molecular Chaperones, The Faseb Journal, pp. 10-19, vol. 10, Jan. 1996.
Butler, J.E., et al.,The Physical and Functional Behavior of Capture Antibodies Adsorbed on Polystyrene, Journal of Immunological Methods, 150 (1992), 77-90.
Caffrey, M., et al.,Biophysical Characterization of gp41 Aggregates Suggests a Model for the Molecular Mechanism of HIV-Associated Neurological Damage and Dementia, The Journal of Biological Chemist, vol. 275, No. 26, Issue of Jun. 30, pp. 19877-19882, 2000.
Chan, D., et al.,Core Structure of gp41 From The HIV Envelope Glycoprotein, Cell, vol., 89, 263-273, Apr. 18, 1997.
Colowick, S.P., and Caplan, N.O., Methods in Enzymology, Academic Press (1980).
Crooke, E., and Wickner, W., Proc. Natl. Acad. Sci. USA 84 (1987) 5216-5220.
Danese, P.N., et al., Genes Dev. 9 (1995) 387-398.
Dartigalongue, C., and Raina, S., Embo J. 17 (1998) 3968-3980.
Dent, A., et al.,The Preparation of Protein-Protein Conjugates, Heterobifunctional Reagents Based on the Biotin-Avidin Interaction, Chapter 5, pp. 261-363.
Doms, R., et al., HIV-1 Membrane Fusion: Targets of Opportunity, The Journal of Cell Biology, pp. F9-F13. vol. 151, No. 2, Oct. 16, 2000.
Ehrnsperger, Monika, et al., Stabilization of Proteins and Peptides in Diagnostic Immunological Assays by the Molecular Chaperone Hsp25, Analytical Biochemistry 259 (1998), pp. 218-225.
Egan, D.A., et al., Biochemistry 32 (1993) 1920-1927.
Endrich, et al.,The V3 Loop of Human Immunodeficiency Virus Type-1 Envelope Protein is a High-Affinity Ligand for Immunophilins Present in Human Blood, Eur. J. Biochem., 252-441-446 (1998).
Fischer, G., et al., Nature 337 (1989) 476-478.
Frech, C., et al.Preferential Binding of an Unfolded Protein to DsbA, The EMBO Journal, vol. 15, No. 2, pp. 392-398, 1996.
Gething, M.,Protein Folding in the Cell, Nature, vol. 355 Jan. 2, 1992.
Glenner, G.G., and Wong, C.W., Biochem. Biophys. Res. Commun. 120 (1984) 885-890.
Glenner, G.G., and Wong, C.W., Biochem. Biophys. Res. Commun. 122 (1984) 1131-1135.
Goethel, S.F., et al.,Peptide-Prolyl Cis-Trans Isomerases, a Superfamily of Ubiquitous Folding Catalysts, Cellular and Molecular Life Sciences (CMLS), pp. 423-436, vol. 55, 1999.
Guyader, M., et al.,Genome Organization and Transactivatioin of the Human Immunodeficiency Virus Type 2, Nature, vol. 326 Apr. 16, 1987.
Hornemann, S., et al., FEBS Lett. 413 (1997) 277-281.
Hottenrott, S., et al., J. Biol. Chem. 272 (1997) 15697-15701.
Iwatsubo, T., et al., Neuron 13 (1994) 45-53.
Ivery, M.T.G., Immunophilins: Switched on Protein Binding Domains? Med Res Rev., Nov. 2000, pp. 452-484.
Kang, J., et al., Nature 325 (1987) 733-736.
Kay, J.E., Biochem J. 314 (1996) 361-385.
Kojouharova, M.S., et al.,Differential Binding of IgG and of a HIV gp41 Peptide by the B Chain and A Chain Globular Head Sequences of C1q, Respectively, Journal of Immunology, 161:4352-4331.
Lane, W.S.,Complete Amino Acid Sequence of the FK506 and Rapamycin Binding Protein, FKBP, Isolated from Calf Thymus, Journal of Protein Chemistry, pp. 151-160, vol. 10, No. 2, 1991.
Lu, Min., et al.,A Trimeric Structural Domain of the HIV-1 Transmembrane Glycoprotein, Nature Structural Biology, pp. 1-8, vol. 2, No. 12, Dec. 1995.
Masters, C.L., et al., Proc. Natl. Acad. Sci. USA 82 (1985) 4245-4249.
Matsubara, Etsuro, et al.,Apolipoprotein J and Alzheimer's Amyloid β Solubility, Biochem J. 316 (1996), pp. 671-679.
Meister, S., et al.,Basic Amino Acid Residues in the V3 Loop of Simian Immunodificiency Virus Envelope Alter Viral Coreceptor Tropism and Infectivity but Do Not Allow Efficient Utilization of CXCR4 as Entry Cofactor, VIROLOGY, 284, 287-296 (2001).
Missiakas, D., et al.,Identification and Characterization of a New Disulfide Isomerase-Like Protein(DsbD)in Escherichia Coli, The EMBO Journal, vol. 14, No. 14, pp. 3415-3424, 1995.
Missiakas, D., et al.,New Components of Protein Foling in Extracytoplasmic Compartments of Escherichia coli SurA, FkpA and Skp/OmpH, Molecular Microbiology, (1996) 21(4), pp. 871-884.
Otteken, et al.Calreticulin Interacts With Newly Synthesized Human Immunodeficiency Virus Type 1 Envelope Glycoprotein, Suggesting A Chaperone Function Similar to That of Calnexin, The Journal of Biological Chemistry, vol. 271, No. 1, Jan. 5, 1996, pp. 97-103.
Pennisi, Elizabeth, Expanding the Eukaryote's Cast of Chaperones, Science, vol. 274, Dec. 1996 pp. 1613-1614.
Prusiner, S.B.,Prions, Nobel Lecture, vol. 95, pp. 13363-1383, Nov. 1998.
Rahfeld, J., et al.,Confirmation of the Existence of a Third Family Among Peptidyl-Prolyl Cisltrans Isomerases Amino Acid Sequence and Recombinant Production of Parvulin, FEBS Letters, 352 (1994) pp. 180-184.
Ramm, K., et al.,The Periplasmic Escherichia coli Peptidylprolyl Cis, Trans-Isomerase FkpA, The Journal of Biological Chemistry, vol., 275, No. 22, Issue of Jun. 2, pp. 17106-17113, 2000.
Ratner, L., et al.,Complete Nucleotide Sequence of the AIDS Virus, HTLV-III, NATURE, pp. 277-284, vol. 313, Jan. 24, 1985.
Roher, A.E., et al., Proc. Natl. Acad. Sci. USA 90 (1993) 10836-10840.
Root, M.J., et al.,Protein Design of an HIV-1 Entry Inhibitor, SCIENCE, pp. 884-888, vol., 291, Feb. 2, 2001.
Schmid, F. X., Molecular chaperones in the life cyle of proteins, eds. A.L. Fink and Y. Goto, Marcel Decker Inc., New York (1998), pp. 361-389.
Scholz, C., et al., Embo J. 16 (1997) 54-58.
Scholz, C., et al., J. Biol. Chem. 271 (1996) 12703-12707.
Selkoe, D.J., et al., J. Neurochem. 46 (1986) 1820-1834.
Selkoe, D.J., J. Neuropath. and Exp. Neurol. 53 (1994) 438-447.
Selkoe, D.J., Neuron 6 (1991) 487.
Speth, C., et al.,A 60 kD Heat-Shock Protein-Like Molecule Interacts with the HIV Transmembrane Glycoprotein gp41, Molecular Immunology, 36 (1999) 619-628.
Stoller, G., et al., Embo J. 14 (1995) 4939-4948.
SWISS-PROT, accession No. P 45523.
Tijssen, In: “Methods in Enzymology”, eds. S.P. Colowick, N.O. Caplan, Academic Press (1980).
Tijssen, P., Preparation of enzyme-antibody or other enzyme-macromolecule conjugates, In: “Practice and theory of enzyme immunoassays”, eds. R.H. Burdon and v. P.H. Knippenberg, Elsevier,

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