Complex suitable for carrying out a method of purifying pre-S he

Details Complex suitable for carrying out a method of purifying pre-S he Complex suitable for carrying out a method of purifying pre-S he

1993-09-03

1994-08-23

Nucker, Christine M.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Conjugate or complex

530412, 530413, 530416, 530417, 5303894, 435 5, 435239, 4242271, A61K 3912, G01N 33569, C12N 702, C07K 312

Patent

active

053405757

ABSTRACT:
There is disclosed a complex comprised of an insoluble polymer carrier to which monomeric human albumin is covalently bound and of a pre-S hepatitis B surface antigen bound in an elutable form to the monomeric human albumin by its pre-S(2)- and/or pre-S(1)-region. This complex may be used for therapeutic and diagnostic purposes and enables the rapid and efficient purification of pre-S-HBsAg by affinity chromatography.

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